Found 42 matching trials
TCR Alpha Beta T-cell and CD19 B-cell Depleted Peripheral Blood Stem Cell Transplantation Using the CliniMACS System for Patients With Non-Malignant Hematologic Disorders From Matched or Mismatched, Related or Unrelated Donors PHASE2 The purpose of this study is to find out if removing a specific type of whi...
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Memorial SloanKettering Cancer Center
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Haploidentical Hematopoietic Stem Cell Transplantation With Ex Vivo TCR Alpha/Beta and CD19 Depletion in Pediatric Hematologic Malignancies PHASE1 This single arm pilot phase I study with safety run-in is designed to estim...
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Washington University School of Medicine
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AlloSCT for Malignant and Non-malignant Hematologic Diseases Utilizing Alpha/Beta T Cell and CD19+ B Cell Depletion PHASE2 Children, adolescents, and young adults with malignant and non-malignant co...
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New York Medical College
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Phase 1/2: CD45RA Depleted Stem Cell Addback to Prevent Viral or Fungal Infections Post TCRab/CD19 Depleted HSCT PHASE1 The major morbidities of allogeneic hematopoietic stem cell transplant (HSC...
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Children's Hospital of Philadelphia
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Memory T-cell Infusion to Improve Immunity After TCR-alpha/Beta Depleted Hematopoietic Stem Cell Transplantation PHASE1 The stud will evaluate whether infusions of CD45RA-depleted lymphocytes fro...
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Federal Research Center for pediatric hematology, oncology and immunology
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Allogeneic Stem Cell Transplant With Alpha/Beta T AND B Cell Depletion for Hematologic Malignancies PHASE2 This is a single arm pilot study for patients using α/β T cell-depleted per...
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Active Not Recruiting
Location
The Children's Hospital of Philadelphia
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KIR Favorable Mismatched Haplo Transplant and KIR Polymorphism in ALL/AML/MDS Allo-HCT Children PHASE2 This is a phase II, open-label, non-randomized, prospective study of haploi...
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Enrolling By Invitation
Location
Children's Hospital Los Angeles
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A Feasibility Study Using CLINIMACS® for Alpha/Beta T-Cell Depletion in Stem Cell Transplant NA Patients in need of an allogeneic hematopoietic cell transplant (HCT) are a...
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University of California, San Francisco
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Haploidentical Hematopoietic Cell Transplantation Using TCR Alpha/Beta and CD19 Depletion NA Patients with medical conditions requiring allogeneic hematopoietic cell tr...
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Active Not Recruiting
Location
Houston Methodist Hospital
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Ex-vivo Primed Memory Donor Lymphocyte Infusion to Boost Anti-viral Immunity After T-cell Depleted HSCT PHASE1 HSCT from an allogeneic donor is the standard therapy for high-risk hematop...
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Federal Research Center for pediatric hematology, oncology and immunology
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